Organ transplant rejection

Transplant rejection occurs when the immune system detects the transplanted organ as foreign.

The immune system protects the body from substances that may be harmful. Antigens are found on the surface of these substances. If the immune system recognizes these antigens as foreign (not part of the body), it will attack them.

Transplant rejection works in the same way. A foreign tissue or organ can trigger a transplant rejection. Organ recipients need to take immunosuppressive drugs to prevent organ rejection.

Last Updated: January 8, 2010

Author: Monica Rhodes

Medical Review: Anne C. Poinier, MD - Internal Medicine & Philip Belitsky, MD, FRCSC - Urology

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