Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare condition in which a tumor called a gastrinoma forms in the pancreas or small intestine. The tumor releases a hormone called gastrin that causes production of excess stomach acid.

Almost all people with Zollinger-Ellison syndrome get an ulcer at some point, usually in the small intestine (duodenal ulcer). Ulcers produced by this disease are more difficult to cure than ulcers from other causes.

In about half of the people with Zollinger-Ellison syndrome, the tumors (gastrinomas) are cancerous and can spread to the lymph nodes and liver.

The main treatment for Zollinger-Ellison syndrome is removal of the tumors and taking acid-suppressing medication called proton pump inhibitors.

Last Updated: April 11, 2008

Author: Monica Rhodes

Medical Review: Kathleen Romito, MD - Family Medicine & Peter J. Kahrilas, MD - Gastroenterology

related physicians

related services

Bon Secours International| Sisters of Bon Secours USA| Bon Secours Health System

This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Privacy Policy. How this information was developed to help you make better health decisions.

© 1995-2010 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.