Symptoms of juvenile rheumatoid arthritis
The most common symptoms of all forms of juvenile rheumatoid arthritis (JRA) include:
- Joint pain and swelling that may come and go but is most often persistent. Symptoms must last for 6 weeks before a diagnosis of JRA can be made.
- Joint stiffness that lasts longer than 1 hour in the morning.
- Irritability, refusal to walk, or protection or guarding of a joint. You might notice your child limping or avoiding the use of a certain joint.
- Often unpredictable changes in symptoms, from periods with no symptoms (remission) to flare-ups.
|Effects of disease||Pauciarticular JRA/Oligoarthritis||Polyarticular JRA/Polyarthritis||Systemic arthritis|
|Joints affected during first 6 months of active disease||
||Joint swelling and pain not necessarily present at onset; eventually affects a few or many joints|
|Joints affected after first 6 months of active disease||
5 or more joints affected
|Increase in number of joints affected over time|
|Whole-body (systemic) symptoms||Not usually||Mild to none||Yes (including once- or twice-daily fever spikes, generalized body pain, rash, mild appetite loss, fatigue, and weakness)|
Yes, in children with polyarthritis who have a certain protein (rheumatoid factor) in their blood
|Eye disease (chronic uveitis)||At least 5 to 15%, with the risk higher in girls than in boys||5%||Rare|
- Warren RW, et al. (2005). Juvenile idiopathic arthritis (Juvenile rheumatoid arthritis). In WJ Koopman, LW Moreland, eds., Arthritis and Allied Conditions, 15th ed., vol. 1, pp. 1277–1300. Philadelphia: Lippincott Williams and Wilkins.
- Cassidy JT (2005). Juvenile rheumatoid arthritis. In ED Harris Jr et al., eds., Kelley's Textbook of Rheumatology, 7th ed., vol. 2, pp. 1579–1596. Philadelphia: Elsevier Saunders.
Last Updated: June 25, 2008