How common is Sjögren's syndrome?

Sjögren's syndrome affects over one million people throughout the United States and is diagnosed in women and men of all races. Rarely occurring in children, Sjögren's syndrome is most common in white women who are in their 40s and 50s. Nine times more women than men have Sjögren's syndrome.1

Sjögren's syndrome may develop in a person who has a connective tissue disorder, such as rheumatoid arthritis, lupus, or scleroderma, and is then classified as secondary Sjögren's syndrome. Secondary Sjögren's syndrome develops in 10% to 25% of people with lupus and in 30% to 50% of people with rheumatoid arthritis.2


  1. Jonsson R, et al. (2005). Sjögren's syndrome. In WJ Koopman, LW Moreland, eds., Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed., vol. 2, pp. 1681–1705. Philadelphia: Lippincott Williams and Wilkins.
  2. Naguwa S, Gershwin ME (2008). Sjögren's syndrome. In L Goldman, D Ausiello, eds., Cecil Textbook of Medicine, 23rd ed., chap. 289, pp. 2041–2045. Philadelphia: Saunders.

Last Updated: May 6, 2008

Author: Shannon Erstad, MBA/MPH

Medical Review: Martin Gabica, MD - Family Medicine & Stanford M. Shoor, MD - Rheumatology

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